CrashPlan PRO supports encrypted volumes/filesystems that are run at a system level. In other words, they are not being configured and run in a user space.
You may run into issues when user-level encrypted file systems if credentials that aren't readily available to CrashPlan PRO.
CrashPlan has full FileVault support. Just make sure you install as the user who owns the FileVault account. Backup will occur only when you're logged into the computer, as that is the only time CrashPlan will be able to see individual files. We support a single FileVault per computer.
There is an option in Truecrypt enabled by default called preserve timestamps of file containers. When enabled, Truecrypt retains the file timestamp from initial file creation. Essentially, it looks like the file has never changed and CrashPlan won't back up the changes. If you disable this option, the file timestamp changes when files are modified, which allows CrashPlan to back up the changes.
In order for CrashPlan PRO to back up or restore files encrypted with EFS, CrashPlan PRO must be installed “as user”. There are instructions for how to do so here.
If you're using another disk encryption product with CrashPlan and have questions or would like to share your knowledge or discuss, please visit our User Forums.
