I've seen it reported that we've found all of the nontrivial zeros to the Riemann zeta function up to some large height, and that all of them have real part $1/2$; i.e. a counterexample would need imaginary part larger than that. But how do we know that we are not missing any zeros?
I found a formula for counting the number of zeros $N(T)$ up to some height $T$:
$$N(T) = \frac{T}{2\pi}\left(\log\frac{T}{2\pi} - 1\right) + O(\log T)$$
Wikipedia says (without citation) and explicit form of the error is:
$$N(T) < \frac{T}{2\pi}\left(\log\frac{T}{2\pi} - 1\right) - \frac{7}{8} + 0.137\log T + 0.443\log\log T + 4.350$$
For illustration, the 3rd zero is reported as having $T=25.01085...$ If we plug that in to the inequality, we get $N(T)<5.95$. So since we only found three zeros, who's to say there aren't 2 zeros hiding out somewhere with real part $\neq 1/2$, imaginary part $<25$? Obviously this gets much more loose when we're talking about zeros up to $10^{20}$ or whatever.