Responding to retinal damage

Latest research

1. 1. Evolutionary Biology

   Structural evolution of nitrogenase enzymes over geologic time

   Bruno Cuevas-Zuviría, Franka Detemple ... Betül Kaçar
2. 1. Cell Biology

   Deletion of sulfate transporter SUL1 extends yeast replicative lifespan via reduced PKA signaling instead of decreased sulfate uptake

   Juan Long, Meng Ma ... Jing Yang
3. 1. Cell Biology

   Efficiency and localisation of AURKA degradation by PROTACs is modulated by deubiquitinases UCHL5 and target-selective OTUD6A

   Annabel Cardno, Karen Roberts, Catherine Lindon
4. 1. Genetics and Genomics

   Chromosome-scale genome assembly of the European common cuttlefish Sepia officinalis

   Simone Rencken, Georgi Tushev ... Gilles Laurent
5. 1. Plant Biology

   Molecular architecture of thylakoid membranes within intact spinach chloroplasts

   Wojciech Wietrzynski, Lorenz Lamm ... Benjamin D Engel
6. 1. Neuroscience

   Separable dorsal raphe dopamine projections mimic the facets of a loneliness-like state

   Christopher R Lee, Gillian A Matthews ... Kay M Tye

   Optogenetic manipulations and neural circuit interrogation reveal that dorsal raphe dopamine circuits can emulate different facets of a loneliness-like state, including prosociality, aversion, and vigilance.
7. 1. Cancer Biology
   2. Chromosomes and Gene Expression

   Conserved and unique features of terminal telomeric sequences in ALT-positive cancer cells

   Benura Azeroglu, Wei Wu ... Eros Lazzerini-Denchi

   Abundant single-stranded telomeric DNA distinguishes alternative lengthening of telomeres-positive cells and represents a potential biomarker and therapeutic vulnerability.
8. 1. Biochemistry and Chemical Biology

   Phage-displayed synthetic library and screening platform for nanobody discovery

   Baolong Xia, Ah-Ram Kim ... Norbert Perrimon

   A phage-displayed synthetic library and screening platform offer a streamlined, cost-effective solution for nanobody discovery.
9. 1. Ecology

   Loss of olfaction reduces caterpillar performance and increases susceptibility to a natural enemy

   Qi Wang, Yufei Jia ... Alexander Haverkamp

   The sense of smell is crucial for insect larvae not only to find a suitable food source but also for finding safe spaces which are free of their natural enemies.
10. 1. Neuroscience

    Interleukin-4 induces CD11c⁺ microglia leading to amelioration of neuropathic pain in mice

    Keita Kohno, Ryoji Shirasaka ... Makoto Tsuda

    Increasing CD11c⁺ microglial subsets in the spinal dorsal horn by intrathecal treatment of interleukin-4 alleviate pain hypersensitivity caused by nerve injury.